Distinguishing poorly differentiated urothelial and
prostatic carcinoma by histomorphology may be sometimes difficult in some cases
with limited TURP resection. Treatment options are different for these malignant
conditions.
IHC staining for androgen receptor is used to
distinguish these two conditions. Intense nuclear stain with higher H-score is
seen in prostatic carcinoma compared to urothelial carcinoma.
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